ER 50 Aspendol Tablet is used to help relieve moderate to severe short-term pain. It contains tapentadol which centrally acts as an analgesic with a dual mechanism of action, combining mu-opioid receptor agonism with noradrenaline reuptake inhibition in the same molecule. It has an improved side effect profile when compared to opioids and nonsteroidal anti-inflammatory drugs. The dual mechanism of action makes ER 50 Aspendol Tablet a useful analgesic to treat acute, chronic, and neuropathic pain. Nonsteroidal anti-inflammatory drugs, opioids, tapentadol hydrochloride